tecovirimat

A potent and specific inhibitor of orthopoxvirus replication. It is used for the treatment of SMALLPOX and other orthopoxvirus infections, including MONKEYPOX under expanded access investigational new drug protocol (https://www.cdc.gov/poxvirus/monkeypox/clinicians/Tecovirimat.html).

Also Known As:

4- trifluoromethyl- N- (3,3a,4,4a,5,5a,6,6a- octahydro- 1,3- dioxo- 4,6- ethenocycloprop(f)isoindol- 2(1H)- yl)- benzamide; N- ((3aR,4R,4aR,5aS,6S,6aS)- 1,3- Dioxo- 3,3a,4,4a,5,5a,6,6a- octahydro- 4,6- ethenocyclopropa(f)isoindol- 2(1H)- yl)- 4- (trifluoromethyl)benzamide; SIGA-246; ST 246; ST-246; TPOXX; benzamide, N- ((3aR,4R,4aR,5aS,6S,6aS)- 3,3a,4,4a,5,5a,6,6a- octahydro- 1,3- dioxo- 4,6- ethenocycloprop(F)isoindol- 2(1H)- yl)- 4- (trifluoromethyl)- , hydrate (1:1), rel-; tecovirimat monohydrate

Organic Chemicals: 140
- Amides: 2487
  - Benzamides: 115
    - tecovirimat: 206
- Hydrocarbons: 1726
  - Cyclic Hydrocarbons: 96
    - Aromatic Hydrocarbons: 295
      - Benzene Derivatives: 17
        Benzoates: 430
        Benzamides: 115
        tecovirimat: 206
- Carboxylic Acids: 986
  - Carbocyclic Acids
    - Benzoates: 430
      - Benzamides: 115
        tecovirimat: 206
    - Phthalic Acids: 1
      - Phthalimides: 14
        tecovirimat: 206
- Imides: 81
  - Phthalimides: 14
    - tecovirimat: 206
Heterocyclic Compounds: 207
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Isoindoles: 20
      - Phthalimides: 14
        tecovirimat: 206

R M L Buller Selected Research

R M L Buller Research Topics

Disease

Drug/Important Bio-Agent (IBA)

Therapy/Procedure